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  • The bacterium that causes Lyme disease can be transmitted to dogs through the bite of an infected tick, most commonly the deer tick (black-legged tick), which is found in the midwestern and eastern United States and throughout Canada. The disease typically causes pain and swelling in the affected dog's joints along with decreased appetite and fever. The kidneys are sometimes affected, in which case the disease is often fatal. Diagnostic testing, treatment, and ways to prevent Lyme disease in your dog, including instructions for tick removal, are explained in this handout.

  • Lymphatic tumors are rare in pets. Lymphangiomas are benign and lymphangiosarcomas are malignant and have a moderate-to-high metastatic potential. Patients with lymphatic tumors typically have severe edema or cavity effusions because of lymphatic obstruction and leakage. These types of tumors occur more frequently in young dogs and cats. Treatment usually involves surgical excision and chemotherapy may be used as a follow-up treatment in the case of lymphangiosarcomas.

  • Lymphocytic plasmacytic gastroenteritis is a form of inflammatory bowel disease. While the exact cause is not known, it is possible that the intestinal bacteria themselves may be involved in stimulating the immune response. Signs include diarrhea, vomiting, loss of appetite, weight loss, and blood in the stool/vomit. Treatment may include nutrition management, immunosuppressive medications, and dietary supplementation of cobalamin, prebiotics, and probiotics.

  • Lymphoma is a cancer of the lymphocytes. Lymphocytes are cells that are involved in the immune system. Feline lymphoma most commonly affects the intestines; therefore, clinical signs of lymphoma are often similar to other intestinal diseases. Diagnosing lymphoma requires finding cancerous cells on microscopic examination. This cancer cannot be prevented, but the likelihood of a cat developing lymphoma can be decreased by preventing feline leukemia virus infection.

  • Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.

  • The most common forms of cutaneous lymphoma are epitheliotropic lymphoma and dermal lymphoma. No specific risk factors or causes have been identified in the development of cutaneous lymphoma. Generally, cutaneous lymphoma can appear as various-sized irritated, ulcerated, or infected patches anywhere on the skin, including the gums, nose, or lip margins. These areas may become ulcerated and bleed, or become crusted. Secondary infections are possible. By far, the most common treatment for cutaneous lymphoma is chemotherapy. Unfortunately, the response to treatment, although initially encouraging, is typically short-lived, with gradual return of the tumors.

  • Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.

  • Bacterial overgrowth is a condition of the small intestine resulting in increased numbers of bowel bacteria. The major concern with bacterial overgrowth is the development of a condition called small intestinal bacterial overgrowth. The bacteria cause damage to the surface of the bowel so digested food cannot be absorbed resulting in malabsorption of nutrients. Malabsorption and SIBO both result in diarrhea but with bacterial overgrowth the diarrhea is chronic. Many cases respond to long term antibiotics.

  • There are several different types of malignant mammary tumors, with carcinomas being the most common. Carcinomas arise from epithelial (skin) cells, tubules of the mammary glands, or other cells found in the mammary chain. The size of the masses and their appearance may vary, but they are usually firm and nodular. Occasionally, the skin over the mass may ulcerate (open) and bleed, and the affected area may feel warm to the touch and become painful. Detecting and treating these tumors when they are small, and before spread has occurred, will provide your dog with the best chance for long-term control.

  • A mammary tumor develops because of abnormal replication of the cells that make up the breast tissue. In cats, most mammary tumors (80-96%) are malignant. Sexually intact cats have a seven-fold increased risk for mammary tumors compared to spayed cats. Detecting and treating these tumors when they are small, and prior to metastasis, provides your cat with the best chance of long-term control. Surgery is by far the best treatment and, given the high metastatic rate in these tumors, chemotherapy is typically pursued afterward.